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decreases the potency of this drug on your body. This may lead to consuming larger amounts of MDMA. Again, save MDMA for special occasions or events only, and use it very sparingly. WARNING: pills in the UK and Europe contain a very high concentration of MDMA. This can lead to accidental overdoses. We recommend that you try half a pill first as it might have much more MDMA than you expect. How often can I take it? The Three Month Rule MDMA works by causing large amounts of serotonin to be released, along with other neurotransmitters like dopamine. After using MDMA, your serotonin levels are lowered, and it takes. There is evidence that MDMA mixed with allergy medicines can cause unpleasant side effects such as sedation. There are also reports of users vomiting and becoming disoriented when combining allergy medicines and MDMA. Using these drugs together can cause an effect stronger than taking them individually, and they aren't likely to cause an adverse or undesirable reaction when used carefully. Additional research should always be done before mixing drugs. There is no evidence to date showing interactions between paracetamol and MDMA. This combination is unlikely to cause an adverse or undesirable reaction when used carefully. There is no evidence to date showing interactions between ibuprofen and MDMA. This combination is unlikely to cause an adverse or undesirable reaction when used carefully. These combinations are considered extremely harmful and should always be avoided. Reactions to combining these drugs are highly unpredictable and can potentially cause death. Serotonin syndrome: increased heart rate, shivering, twitching, over-responsive reflexes, extremely high temperatures. Decreased appetite Visual distortion: mild hallucinations Rapid involuntary eye jiggling Change in body temperature regulation Unexpected emotions Strong desire to take more MDMA when coming down. PMMA in a pill that was thought to be MDMA. We know some people cannot be bothered to test, but it is becoming increasingly important to do this in order to stay safe. Check the interactions Check our drug interaction chart above! These combinations are not usually harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Be careful when mixing these drugs. Some people experience a 'loss of magic' after using MDMA after a couple of uses, meaning the drug doesn't feel as good as the first few times. However, this does not happen to all people. If MDMA is taken on successive days or weeks, then the negative and comedown effects are worsened. Additional harm reduction advice Drink plenty of water before and after, and we also recommend taking vitamin supplements. Here is. Fuzzy memory Decrease in attention or difficulty concentrating Some people feel happier in general and more focused. Mild to strong depression. Using these drugs together can cause an effect stronger than taking them individually, and they aren't likely to cause an adverse or undesirable reaction when used carefully. Additional research should always be done before mixing drugs. These combinations are not usually harmful, but may produce undesirable effects, such as physical discomfort or overstimulation. Extreme use may cause physical health issues. Be careful when mixing these drugs. Using these drugs together can cause an effect stronger than taking them individually, and they aren't likely to cause an adverse or undesirable reaction when used carefully. Additional research should always be done before mixing drugs. MDMA is a stimulant-hallucinogenic research chemical originally created in 1912 by Merck. It gained popularity in the 1980s rave/dance scene and is especially known for being a potent empathogen. MDMA is commonly sold in powder form, thought to be purer than pills ('ecstasy'). The contents of ecstasy pills are unpredictable and can be a combination of MDMA, caffeine, MDA, methamphetamine, ketamine and many others. Aspirin and MDMA taken together may cause a greater increase in body temperature and sweating than is normal. This poses the greatest risk when dancing in crowded conditions. Take a break periodically to cool down. Do not doubt to call a paramedic if you feel any of these symptoms. You will not get into trouble. Effects are additive. The combination is unlikely to cause any adverse or undesirable reactions beyond those that might ordinarily be expected from taking these drugs individually. How you take it matters. Orally MDMA usually comes in a powder or pill form, and is ingested orally. Nasally MDMA is also sometimes taken nasally. The effects take shorter to appear, but this is not recommended, as it decreases the length of the experience, cause nasal pain and can cause a more severe comedown. If you were to snort MDMA, make sure the powder/crystal is finely crushed. Clean your nostrils after snorting and alternate them if snorting more than once. How much? Using these drugs together can cause an effect stronger than taking them individually, and they aren't likely to cause an adverse or undesirable reaction when used carefully. Additional research should always be done before mixing drugs. Test the drug MDMA and ecstasy are often mixed with other chemicals, from caffeine to methamphetamine. We recommend that you always test your pills using a.